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Julien Ochala – Towards a treatment for myosinopathies
Le CERMO-FC a le plaisir de vous inviter à la présentation du Pr Julien Ochala, Professeur associé à l’Université de Copenhague, et nouveau membre associé du CERMO-FC. Ses travaux de recherche vous seront présentés par visioconférence le Jeudi 5 mai 2022 à 12h00.
CERMO-FC is pleased to invite you to the presentation of Pr Julien Ochala, Associate professor at the University of Copenhagen, and new associate member of CERMO-FC. His research work will be presented to you by videoconference on Thursday May 5, 2022 at 12:00 p.m.
Portrait of the Pr Julien Ochala
Towards a treatment for myosinopathies
Abstract: Over 40% of the human body is made up of skeletal muscles. These are composed of numerous cells called muscle fibres. Within the myofibres, one main protein called myosin drives force production and motion. Genetic alterations to the MYH7 and MYH2 genes that encode part of the myosin molecule lead to rare muscle diseases known as congenital myopathies or myosinopathies. In the present research seminar, Julien Ochala will present what we know about these faulty (or mutant) myosin proteins and how they induce human pathological states. Current experimental treatments will also be discussed.
Biography: After PhD studies at the University of Burgundy (France) and postdoc at Uppsala University (Sweden), Julien Ochala became a principal investigator at King’s College London (UK). Using X-ray diffraction together with a unique combination of myofibre mechanics and cell biological methods, his team elucidated important mechanisms by which some mutations in muscle contractile proteins result in muscle weakness and rare neuromuscular diseases. They also identified potential novel AAV-related gene therapies for these specific mutations. Julien Ochala and his group recently relocated to the University of Copenhagen and they are pursuing similar lines of research.
Un évènement organisé dans le cadre des Pause-conférences du CERMO-FC
An event organized as part of the Pause-conférences of CERMO-FC
