Genomics core

The genomics platform will accompany you in your genomic, metagenomic and transcriptomic sequencing project. Sequencing or resequencing of small genomes (bacteria, virus, yeast), transcriptome and amplicons can be done from sample preparation to data acquisition. Subsequently, the bioinformatics platform can offer you a data analysis service (more details here).

For more information please contact us at the following address: genomique.cermofc@uqam.ca


Bioinformatics core

The bioinformatics platform supports the main data analyzes resulting from the high throughput sequencing. The services offered cover a wide range of services.

For more information please contact us at the following address:  bioinfo.cermofc@uqam,ca


Transgenic and genome editing core

This platform offers the possibility to generate genetically modified mouse models at low cost. The service includes conventional microinjection, either the random insertion of a gene, or targeted modifications with the CRISPR / Cas9 method. In addition, complementary services such as the cryopreservation of lineage (sperm or embryos) and the regeneration of lineage by IVF (from sperm or frozen embryos) are available.

For more information please contact us at the following address:  transgene.cermofc@uqam.ca


Cellular analysis and imaging core

This platform offers complete and integrated photonic imaging and flow cytometry. Our technical staff ensures personalized support and training adapted to the needs of each user. Using microscopy and flow cytometry equipment, this platform allows 1) to indentify and track real-time  molecular markers, and 2)  cell subpopulation isolationfor  for analysis or cell culture. Thus, the cellular analysis and imaging core allows to characterize of phenotypes and elucidate molecular mechanisms.

For more information please contact us at the following address:  cell.cermofc@uqam.ca


Mass Spectrometry core

This platform allows the analysis of chemical and biological molecules as well as proteomic and metabolomic analyzes. This platform includes 3 mass spectrometers coupled to liquid chromatography systems ; HPLC-MS-TOF, HPLC-MS-MS (triple quadrupole, low resolution) and HPLC-MS/MS (quadrupole-flight time, high resolution).

For more information please contact us at the following address:  ms.cermofc@uqam.ca


Biophysics and biomolecular screening core

This multidisciplinary platform allows the identification and validation of therapeutic targets and molecules specifically targeting these biological targets. In particular, this platform allows (i) chemical and functional screening using different biological and cellular assays as well as (ii) the complete characterization of interactions (affinity, binding mechanisms, structure) between biomolecules by different biophysical approaches. A peptide synthesis service is also offered.

For more information please contact us at the following address:  biophys.cermofc@uqam.ca